PCAC: Preserve Transdermal and Other Natural Medicines

The FDA’s Pharmacy Compounding Advisory Committee (PCAC) has announced its next meeting, where it will make recommendations on whether any of five specific substances will be allowed. The likelihood of their recommendation not being followed is remote.

The five substances being reviewed are diindolylmethane (DIM), trichloroacetic acid, kojic acid, glycolic acid, and vasoactive intestinal peptide.

DIM is especially important. It is a naturally occurring compound found in Brassica vegetables like Brussels sprouts, cabbage, mustard greens, and kale, and has anti-cancer and immune-modulating properties. DIM can prevent hormone-related cancers, including breast and prostate cancer. It works, in part, by altering ratios of “good” and “bad” estrogen—reversing the effect, for example, of dihydrotestosterone, which is associated with prostate cancer.

Write to PCAC and tell them to maintain consumer access to these important medicines!


  • Food and Drug Administration


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Please preserve access to important natural medicines

Dear [Decision Maker],

[Your Name]
[Your Address]
[City, State ZIP]